Tubulin in vitro, in vivo and in silico

Show simple item record

dc.contributor.advisor Nanopoulos, Dimitri V. en_US
dc.creator Mershin, Andreas, 1975- en_US
dc.date.accessioned 2005-02-17T21:08:45Z
dc.date.available 2005-02-17T21:08:45Z
dc.date.created 2003-12 en_US
dc.date.issued 2005-02-17T21:08:45Z
dc.identifier.uri http://handle.tamu.edu/1969.1/1635
dc.description.abstract Tubulin, microtubules and associated proteins were studied theoretically, computationally and experimentally in vitro and in vivo in order to elucidate the possible role these play in cellular information processing and storage. Use of the electric dipole moment of tubulin as the basis for binary switches (biobits) in nanofabricated circuits was explored with surface plasmon resonance, refractometry and dielectric spectroscopy. The effects of burdening the microtubular cytoskeleton of olfactory associative memory neurons with excess microtubule associated protein TAU in Drosophila fruitflies were determined. To investigate whether tubulin may be used as the substrate for quantum computation as a bioqubit, suggestions for experimental detection of quantum coherence and entanglement among tubulin electric dipole moment states were developed. en_US
dc.description.provenance Made available in DSpace on 2005-02-17T21:08:45Z (GMT). No. of bitstreams: 1 etd-tamu-2003C-PHYS-Mershin-1.pdf: 1769122 bytes, checksum: 50c5c850c4b8dd0ca5cef4c3ba10c2f0 (MD5) en
dc.format.extent 1769122 bytes
dc.format.medium electronic en_US
dc.format.mimetype application/pdf
dc.language.iso en_US en_US
dc.publisher Texas A&M University en_US
dc.subject tubulin en_US
dc.subject microtubules en_US
dc.subject dielectric en_US
dc.subject spectroscopy en_US
dc.subject surface en_US
dc.subject plasmon en_US
dc.subject resonance en_US
dc.subject simulation en_US
dc.subject drosophila en_US
dc.subject memory en_US
dc.subject olfactory en_US
dc.subject quantum en_US
dc.subject brain en_US
dc.subject qubit en_US
dc.subject biobit en_US
dc.subject bioqubit en_US
dc.subject teleportation en_US
dc.subject refractometry en_US
dc.subject dipole en_US
dc.subject moment en_US
dc.subject protein en_US
dc.title Tubulin in vitro, in vivo and in silico en_US
thesis.degree.department Physics en_US
thesis.degree.discipline Physics en_US
thesis.degree.grantor Texas A&M University en_US
thesis.degree.name Ph. D. en_US
thesis.degree.level Doctoral en_US
dc.contributor.committeeMember Kattawar, George W. en_US
dc.contributor.committeeMember Schuessler, Hans A. en_US
dc.contributor.committeeMember Zoran, Mark J. en_US
dc.type.genre Electronic Dissertation en_US
dc.type.material text en_US
dc.format.digitalOrigin born digital en_US

Files in this item

Files Size Format View
etd-tamu-2003C-PHYS-Mershin-1.pdf 1.769Mb application/pdf View/Open

This item appears in the following Collection(s)

Show simple item record